African sleeping sickness: Study suggests new way to help the immune system fight off parasite

African sleeping sickness, caused by the parasite Trypanosoma brucei, is transmitted by the tsetse fly and is fatal if left untreated. New research reveals a method to manipulate trypanosomes in the mammalian bloodstream to acquire fly stage characteristics. The findings suggest that inhibiting specific proteins can 'trick' the parasite into differentiating to a different stage of its lifecycle.